CONVERGENT, FUNCTIONALLY INDEPENDENT SIGNALING BY MU AND DELTA OPIOID RECEPTORS IN HIPPOCAMPAL PARVALBUMIN INTERNEURONS

Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons

Functional interactions between G protein-coupled receptors are poised to enhance neuronal sensitivity to neuromodulators and therapeutic drugs.Mu and delta opioid receptors (MORs and DORs) can interact when overexpressed in the same cells, but whether co-expression of endogenous MORs and DORs in neurons leads to functional interactions is unclear.

read more

Methyl (2Z)-2-bromomethyl-3-(2,4-dichlorophenyl)prop-2-enoate

In the title compound C11H9BrCl2O2, which represents the Z outre x-pression twisted up - passion water wave 24 isomer, the methylacrylate moiety is essentially planar within 0.039 (2) Å and has an extended trans configuration.The benzene ring makes a dihedral angle of 28.3 (1)° with the mean plane of hollowbet the methyl

read more

Unveiling the royal road to happiness: the predictive role of psychological hardiness, mediated by vitality and materialistic values

The quest for happiness is highly esteemed in every culture.Based on the theory of the positive activity model, the current study examined the role of psychological hardiness in happiness among youth.The study also investigated the parallel mediating role of vitality and materialistic values in the relationship between psychological hardiness and h

read more